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originally posted by: MonkeyBalls2
originally posted by: Byrd
originally posted by: Irishhaf
So odd thoughts, shouldn't we be just as worried about our eyes as breathing in the virus? I seem to remember from chem warfare training that biological weapons could get in through eyes, ears, mouth, and any openings on the skin.
Could obviously be wildly off base, just a random thought as I left the commissary and some retired guy was giving the airmen at the door heck for not letting him in without a mask.
It's a respiratory virus. It can't get in via the digestive system, ears, eyes, or pores on the skin.
Your eyes are connected to your nose, iirc.
It would probably take liquid transfer though, not just floating particles wafting in the air.
originally posted by: FormOfTheLord
So it would seem that the virus attacks T cells and thus destroys the immune system. This virus looks deadly.
www.scmp.com...
Coronavirus could target immune system by targeting protective cells, warn scientists
Researchers in China and the US find that the virus that causes Covid-19 can destroy the T cells that are supposed to protect the body from harmful invaders
One doctor said concern is growing in medical circles that effect could be similar to HIV
The coronavirus that causes Covid-19 could kill the powerful immune cells that are supposed to kill the virus instead, scientists have warned.
The surprise discovery, made by a team of researchers from Shanghai and New York, coincided with frontline doctors’ observation that Covid-19 could attack the human immune system and cause damages similar to that found in HIV patients.
Doctors who had seen the bodies said the damage to the internal organs was similar to a combination of Sars and Aids.
The gene behind the fusion function in Sars-CoV-2 was not found in other coronaviruses in human or animals.
But some deadly human viruses such as Aids and Ebola have similar sequences, prompting speculation that the novel coronavirus might have been spreading quietly in human societies for a long time before causing this pandemic.
originally posted by: Arbitrageur
originally posted by: Byrd
It's a respiratory virus. It can't get in via the digestive system, ears, eyes, or pores on the skin.
COVID-19 May Be Transmitted Through the Eye, Report Finds
They call it a respiratory virus, then say it might be transmitted through the eye.
A new report published by JAMA Ophthalmology found preliminary data may suggest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), might be transmitted through the eye.
Researchers analyzed data from 38 patients infected with COVID-19 from Hubei Province, China, and found 12 (31.6%; 95% CI, 17.5%-48.7%) individuals had ocular manifestations, including epiphora, conjunctival congestion, or chemosis.
These symptoms commonly occur in patients with severe systemic manifestations of COVID-19 and are consistent with conjunctivitis, or pink eye.
You're probably right about it not transmitting through the skin, but you may be wrong about the eye. The expert from S. Korea said what this virus needs to transmit is a mucous membrane, which is not present on the skin, so he confirmed the skin can't transmit it.
This is the same expert from S. Korea video that was posted several times in part 5 of the updates thread. He talks about how the virus needs a mucous membrane for transmission:
You Need To Listen To This Leading COVID-19 Expert From South Korea
starting at 15 minutes in the video:
"You said the virus can infect you through your eyes. (If the virus can get in through your eyes, what's the point of wearing a mask?)
I mentioned eyes, nose and mouth because there are mucous membranes inside them.
These mucous membranes have a receptor called ACE2. The virus has to stick to those receptors. We don't have receptors on our skin. Our skin actually acts as a sort of barrier. The virus can't go through your ears"
originally posted by: Byrd
It's a respiratory virus. It can't get in via the digestive system, ears, eyes, or pores on the skin.
In the digestive system, besides esophagus upper and stratified epithelial cells, ACE2 was also found in the absorptive enterocytes from ileum and colon, the most vulnerable intestinal epithelial cells. In microbe infections, the intestinal epithelial cells function as a barrier and help to coordinate immune responses[35]. The absorptive enterocytes can be infected by coronavirus, rotavirus and noroviruses, resulting in diarrhea by destructing absorptive enterocytes, malabsorption, unbalanced intestinal secretion and activated enteric nervous system[36-38]. Thus, we suppose that the enteric symptom of diarrhea might be associated with the invaded ACE2-expressing enterocytes. In addition, due to the high expression of cell receptor ACE2 in esophagus upper and stratified epithelial cells and absorptive enterocytes from ileum and colon, we suppose that digestive system can be invaded by 2019-nCov and serve as a route of infection.
www.biorxiv.org...
Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag
The majority of patients with severe coronavirus symptoms using Gilead's remdesivir showed "clinical improvement" in a compassionate use trial the company said.
Biotechnology titan Gilead Sciences (GILD) - Get Report Friday announced a successful trial of its antiviral drug to treat the coronavirus -- remdesivir
The results came from a cohort analysis of 53 hospitalized patients suffering severe coronavirus symptoms who were treated with remdesivir on an individual compassionate use basis. The drug hasn’t been approved for general use by the Food and Drug Administration.
“The majority of patients in this international cohort demonstrated clinical improvement and no new safety signals were identified with remdesivir treatment,” Gilead said in a statement.
originally posted by: anonentity
a reply to: Cloudbuster
At this rate their will be no cases in NZ , the economy will be up and running, While some countries are still debating if a full lockdown works.
This is a real scientific clinical trial
"We look forward to the results of controlled clinical trials to potentially validate these findings."
originally posted by: jadedANDcynical
originally posted by: Byrd
It's a respiratory virus. It can't get in via the digestive system, ears, eyes, or pores on the skin.
In the digestive system, besides esophagus upper and stratified epithelial cells, ACE2 was also found in the absorptive enterocytes from ileum and colon, the most vulnerable intestinal epithelial cells. In microbe infections, the intestinal epithelial cells function as a barrier and help to coordinate immune responses[35]. The absorptive enterocytes can be infected by coronavirus, rotavirus and noroviruses, resulting in diarrhea by destructing absorptive enterocytes, malabsorption, unbalanced intestinal secretion and activated enteric nervous system[36-38]. Thus, we suppose that the enteric symptom of diarrhea might be associated with the invaded ACE2-expressing enterocytes. In addition, due to the high expression of cell receptor ACE2 in esophagus upper and stratified epithelial cells and absorptive enterocytes from ileum and colon, we suppose that digestive system can be invaded by 2019-nCov and serve as a route of infection.
The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes
originally posted by: Phage
a reply to: Willtell
This is a real scientific clinical trial
No it isn't. There were no blinds and there were no controls.
Your source:
"We look forward to the results of controlled clinical trials to potentially validate these findings."
Gilead Sciences Inc.’s experimental drug for patients with severe Covid-19 infections showed promise in an early analysis, raising tentative hope that the first treatment for the novel virus may be on the horizon.
The report published in the New England Journal of Medicine tracked 53 people in the U.S., Europe and Canada who needed respiratory support, with about half receiving mechanical ventilation and four on a heart-lung by-pass machine. Eight additional patients were left out of the analysis: one due to a dosing error and seven because no information was available on how they fared.
Biotechnology titan Gilead Sciences (GILD) - Get Report Friday announced a successful trial of its antiviral drug to treat the coronavirus -- remdesivir
Gilead Sciences Inc.’s experimental drug for patients with severe Covid-19 infections showed promise in an early analysis, raising tentative hope that the first treatment for the novel virus may be on the horizon.
The report published in the New England Journal of Medicine tracked 53 people in the U.S., Europe and Canada who needed respiratory support, with about half receiving mechanical ventilation and four on a heart-lung by-pass machine. Eight additional patients were left out of the analysis: one due to a dosing error and seven because no information was available on how they fared.
Gilead’s experimental drug remdesivir shows ‘hopeful’ signs in small group of coronavirus patients
Two-thirds of severely ill patients showed some improvement when treated with the antiviral medicine.
scholar.google.au
The possible origins of 2019-nCoV coronavirus
In summary, somebody was entangled with the evolution of 2019-nCoV coronavirus.
In addition to origins of natural recombination and intermediate host, the killer coronavirus
probably originated from a laboratory in Wuhan. Safety level may need to be reinforced in
high risk biohazardous laboratories. Regulations may be taken to relocate these
laboratories far away from city center and other densely populated places.
scholar.google.au
The probability was very low for the
bats to fly to the market. According to municipal reports and the testimonies of 31 residents
and 28 visitors, the bat was never a food source in the city, and no bat was traded in the
market
observers.france24.com...
Is bat soup a delicacy in China? We debunk a rumour on the origin of the coronavirus
However, our team reached out to several specialists in Chinese culinary traditions, who all said that people in China don’t tend to eat bat meat.
Guansheng Ma is the director of Nutrition and Gastronomy at the University of Beijing.
"According to our research, eating bat meat is more than rare in China. It’s actually unacceptable in Chinese culture."
Our Observer Lu Haitao grew up in Wuhan but now lives in Beijing. He agreed.
"I have never seen bat meat for sale in markets or restaurants in Wuhan or elsewhere in China. I’ve also never heard anyone talk about eating it. For me, eating bat meat is both inconceivable and disgusting."
William Chan Tat Chuen, an expert in Chinese cuisine, is the author of a book about exchanges between French and Chinese culinary traditions. He agreed with our other Observers, though he did say that bat excremement is occasionally used in Chinese medicine:
"Chinese medicine uses bat excrement to improve patients’ vision and to treat dysentery, hemorrhages and diarrhea. It is often mixed into rice porridge or made into a kind of tea. However, I don’t know anyone who has actually used this treatment. Similarly, none of my Chinese friends or family eat bat meat. Chinese medicine doesn’t say anything about eating it.
That said, people in China have a different vision of bats than people in Europe. In China, bats represent happiness and people aren’t disgusted by them."
originally posted by: Phage
a reply to: Willtell
Posting different versions of the same story doesn't change the fact that it was not "a real scientific clinical trial ."
More research might clarify that, but even if it's just pink eye resulting from the viral infection at first, think about people rubbing their eyes and then with the virus on their fingers touching their nose and or mouth. So it may not stay isolated as pink eye even if it starts that way. There may be other routes to pass from the eye to the respiratory system too.
originally posted by: Byrd
There's not much followup on that, and it was associated with pink eye type symptoms. I think that it might (under very unusual conditions) be found in the eye and even infect the eye, but I don't think that it's transmitted that way.