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Hydroxychloroquine and Azithromycin as a treatment of COVID-19 Promising Trial

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posted on Mar, 21 2020 @ 05:00 PM
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Here's a promising study. Maybe it's time to start treating coronavirus.

Hydroxychloroquine and Azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial


Abstract

Background Chloroquine and Hydroxychloroquine have been found to be efficient on COV-19, and reported to be efficient in Chinese patients infected by this virus. We evaluate the role of Hydroxychloroquine on respiratory viral loads. Patients and methods Patients were included in a single arm protocol to receive 600mg of hydroxychloroquine daily and their viral load in nasal swabs was tested daily. Depending on their clinical presentation azithromycin was added to the treatment. Untreated patients from another center and cases refusing the protocol were included as negative control. Presence and absence of virus at Day-6 was considered the end point. Results Twenty cases were treated in this study and showed a significant reduction of the viral carriage at D-6 compared to controls, and much lower than reported average carrying duration of untreated patients in the literature. Azithromycin added to Hydroxychloroquine was significantly more efficient for virus elimination. Conclusion : Hydroxychloroquine is significantly associated with viral load reduction/disappearance in patients with COVID-19 and its effect is reinforced by Azithromycin.


www.medrxiv.org...

Maybe this is why China's domestic cases of Coronavirus has dropped to zero even though imported infections are growing.




posted on Mar, 21 2020 @ 05:07 PM
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a reply to: neoholographic

It is in practice in South Korea and working well.

We found something that sticks to the wall.



posted on Mar, 21 2020 @ 05:32 PM
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a reply to: neoholographic

Going to pick a variety of fungi tomorrow, mainly Trametes Versicolor, easy to find in winter.

I have been taking small dozes of mushrooms and cacti for a week now,

Some species have this weird effect, they make you cough up all the mucus that is normally sitting at the bottom of my lungs.

And many of them boost immunity, are antiviral, and induce neurogenesis, so they are a healthy snack anyways.

-Polypores are easy to find this time of the year, 99% of them are good to go, powder in food, or tea, but stay away from Hapalopilus nidulans, because then you will have more to worry about than just purple pee (No joke).


edit on 21-3-2020 by solve because: (no reason given)



posted on Mar, 21 2020 @ 05:47 PM
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originally posted by: neoholographic
Maybe this is why China's domestic cases of Coronavirus has dropped to zero even though imported infections are growing.


i think it's more because China quarantined the infected cities and cut off the virus from new hosts to spread to when only thousands were infected, these drugs haven't been used outside of clinical trials yet from what I've read. i also think it's too early to tell if China has been successful yet in stopping it, the real test will come when people return to work, school and start intermingling again like before.

quality of healthcare means nothing to viruses until you have a vaccine, until then you can only isolate people and treat the sick, treatment isn't the problem though, the problem is that even with treatment the system will still be overwhelmed with treating so many people when the wave hits. it's great that drug trials seem successful so far but whether it's actually effective on a large scale or not will be another matter, even then we can only treat so many so fast when these drugs hit full production.

it really depends on what governments are willing to do or what the people are willing to do to prevent it's spread, that's all anyone can do even with treatments. hope is great and all but being too positive too soon will only create anger and suspicion when people realize that treatment isn't the big cure they assumed it was.



posted on Mar, 21 2020 @ 06:37 PM
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a reply to: namehere

You can think whatever you want but :Conclusion : Hydroxychloroquine is significantly associated with viral load reduction/disappearance in patients with COVID-19 and its effect is reinforced by Azithromycin.

And the OP isn't the only source, there's more. This drive for another unneeded vaccine gets my hairs up Does the Coronavirus Pandemic Serve a Global Agenda? • Children's Health Defense
childrenshealthdefense.org...
edit on 21-3-2020 by BlueJacket because: (no reason given)

edit on 21-3-2020 by BlueJacket because: (no reason given)



posted on Mar, 21 2020 @ 10:25 PM
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Chlorquine getting bought up

It looks like people (health care facilities) everywhere in the world are buying up all the chloroquine they can get their hands on.

Interesting, and there is already a shortage according to the article above.
edit on 21-3-2020 by NoCorruptionAllowed because: edit



posted on Mar, 21 2020 @ 10:55 PM
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Media is spewing that Trump is pushing unproven treatments. That is not the case, there is evidence already that it works. But we should be cautious too, and Trump even stated that when I watched the update on TV. He said they ordered a million doses of Chloroquinine already, the Zpacs are no problem. It is a common medicine.

The News is still pushing political bias, they should have their license taken away. If they convince Democrats not to take this combo that could save their life and not listen to their doctors, then there will be way less Democrats in this country. By saying way less, I mean a thousand, because not that many are dying from the virus that even vote anymore. seventy and eighty year olds in a weakened state don't feel like going out and voting, but it does not stop their kids from voting for them.



posted on Mar, 21 2020 @ 11:05 PM
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There are cures for cancer that have been hidden for decades, because a cure is not part of the agenda.

A cure for Corona Virus is not part of the agenda either.



posted on Mar, 21 2020 @ 11:05 PM
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For once( and this is a miracle) I agree with Trump. It's nothing wrong with them trying this drug and pushing it if it has great potential.

Everything I've read is positive and hopeful about it. And there's one out of Cuba that also is working according to a lot of reporting. Cuban drug used against coronavirus in China available in Panamamenafn.com...

Sure, let them do their trials but meanwhile GET THE DRUGS TO THE SICK!

It certainly can't hurt.



posted on Mar, 21 2020 @ 11:10 PM
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a reply to: Willtell

This.

Chloroquine and azithro have been around for long enough that we know they are safe and generally well tolerated by most everyone. They risks and side effects are known because they've been used in other cases for so long.

It's not like they're brand-spanking new.

THey only unknown is their specific efficacy in this instance, and using it in this instance will allow you to do that study.



posted on Mar, 21 2020 @ 11:15 PM
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a reply to: Willtell




For once( and this is a miracle) I agree with Trump. It's nothing wrong with them trying this drug and pushing it if it has great potential.

Until, and unless, it is approved for treatment of COVID19 it can only be used on terminal patients and that use does not constitute a clinical trial.

Trump, umm, misspoke (yeah, that's it) when he said it was approved for treatment.

That said, various drugs are sometimes employed for "off label" use, illegally.

edit on 3/21/2020 by Phage because: (no reason given)


(post by MotherMayEye removed for political trolling and baiting)

posted on Mar, 21 2020 @ 11:21 PM
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a reply to: Phage

Huh, so I have terminal migraine? Doctors prescribe things that show promise but haven't exactly been approved by the FDA as official treatments all the time.



posted on Mar, 21 2020 @ 11:21 PM
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a reply to: ketsuko

Not legally.

My oncologist offered THC pills to me 30 or so years ago. Illegally.
edit on 3/21/2020 by Phage because: (no reason given)



posted on Mar, 21 2020 @ 11:22 PM
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originally posted by: Phage
a reply to: Willtell




For once( and this is a miracle) I agree with Trump. It's nothing wrong with them trying this drug and pushing it if it has great potential.

Until, and unless, it is approved for treatment of COVID19 it can only be used on terminal patients.

Trump, umm, misspoke (yeah, that's it) when he said it was approved for treatment.

That said, various drugs are sometimes employed for "off label" use.


Yep.

Unless the patient is part of one of the various new clinical trials.

Seems a lot of people don't understand the difference between a legitimate therapy/treatment and a desperate, or the approving family of a desperate "Guinee Pig".


edit on 21-3-2020 by Sookiechacha because: (no reason given)



posted on Mar, 21 2020 @ 11:24 PM
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It's not like they're brand-spanking new.
a reply to: ketsuko

That doesn't seem to be how Big Pharma operates. I fully expect them to slightly alter the ingredients or add one, package it specifically for COV=19 and charge thousands. For those who can't pay, the government will reimburse the the manufacturer.



posted on Mar, 21 2020 @ 11:24 PM
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a reply to: ketsuko

Yeah, like a shot glass of colloidal silver? Go ahead! What the hell do you have to lose?



posted on Mar, 21 2020 @ 11:27 PM
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a reply to: Phage

If a medication is approved and safe for a use, a doctor can prescribe it off-label for another use it has shown promise in treating.

That's how I originally wound up on topamax. It was and is primarily an anti-seizure drug, but at the time I wound up on it, migraine specialists were using it for migraine prophylaxis off-label. At this point, it has been well over 10 years, so it may be approved for that use by now, but at the time, it wasn't. It was widely known that it was happening.



posted on Mar, 21 2020 @ 11:31 PM
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www.cdc.gov...


. A study in China reported that chloroquine treatment of COVID-19 patients had clinical and virologic benefit versus a comparison group, and chloroquine was added as a recommended antiviral for treatment of COVID-19 in China [6].Based upon limited in-vitro and anecdotal data, chloroquine or hydroxychloroquine are currently recommended for treatment of hospitalized COVID-19 patients in several countries. Both chloroquine and hydroxychloroquine have known safety profiles with the main concerns being cardiotoxicity (prolonged QT syndrome) with prolonged use in patients with hepatic or renal dysfunction and immunosuppression but have been reportedly well-tolerated in COVID-19 patients.
a reply to: Phage

It's being used in other countries including China. This one and others might be at this point requested for compassionate use. To my knowledge, a doctor can prescribe one medicine even though it's not precisely approved by the FDA for that particular pathology.



posted on Mar, 21 2020 @ 11:32 PM
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a reply to: ketsuko

I concur. Twas I who, umm, misspoke in this case.


You may be asking yourself why your healthcare provider would want to prescribe a drug to treat a disease or medical condition that the drug is not approved for. One reason is that there might not be an approved drug to treat your disease or medical condition. Another is that you may have tried all approved treatments without seeing any benefits. In situations like these, you and your healthcare provider may talk about using an approved drug for an unapproved use to treat your disease or medical condition.

www.fda.gov...

If a treatment has been approved, it has also been deemed safe as part of the approval process. Safe if used within certain parameters, I suppose.

edit on 3/21/2020 by Phage because: (no reason given)



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