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originally posted by: Irishhaf
If it was an accidental leak obviously they are not seeing a concentrated dose in a specific area, which would change the projected reactions.
Also Italy called they would like to have a word...
"By comparing the available genome sequence data for known coronavirus strains, we can firmly determine that SARS-CoV-2 originated through natural processes," said Kristian Andersen, Ph.D., an associate professor of immunology and microbiology at Scripps Research and corresponding author on the paper.
originally posted by: Irishhaf
Outside of China it has come to each country in dribs and drabs, if you wanted to use it as a weapon you would want to "seed" as many areas in a city or country as possible as close to the same time frame to get a spike in cases quickly.
instead we got dribs and drabs in different areas getting an uneven rise in cases, allowing some places to actually get ready rather than a surprise butt sexxors moment.
The scientists analyzed the genetic template for spike proteins, armatures on the outside of the virus that it uses to grab and penetrate the outer walls of human and animal cells. More specifically, they focused on two important features of the spike protein: the receptor-binding domain (RBD), a kind of grappling hook that grips onto host cells, and the cleavage site, a molecular can opener that allows the virus to crack open and enter host cells.
The scientists found that the RBD portion of the SARS-CoV-2 spike proteins had evolved to effectively target a molecular feature on the outside of human cells called ACE2, a receptor involved in regulating blood pressure. The SARS-CoV-2 spike protein was so effective at binding the human cells, in fact, that the scientists concluded it was the result of natural selection and not the product of genetic engineering.
This evidence for natural evolution was supported by data on SARS-CoV-2's backbone—its overall molecular structure. If someone were seeking to engineer a new coronavirus as a pathogen, they would have constructed it from the backbone of a virus known to cause illness. But the scientists found that the SARS-CoV-2 backbone differed substantially from those of already known coronaviruses and mostly resembled related viruses found in bats and pangolins.
The researchers proposed bats as the most likely reservoir for SARS-CoV-2 as it is very similar to a bat coronavirus. There are no documented cases of direct bat-human transmission, however, suggesting that an intermediate host was likely involved between bats and humans.
In this case, the current epidemic would probably have emerged rapidly as soon as humans were infected, as the virus would have already evolved the features that make it pathogenic and able to spread between people.
In the other proposed scenario, a non-pathogenic version of the virus jumped from an animal host into humans and then evolved to its current pathogenic state within the human population.
Then the other distinct spike protein characteristic of SARS-CoV-2, the cleavage site, could have evolved within a human host, possibly via limited undetected circulation in the human population prior to the beginning of the epidemic.
The virus originated in bats and then jumped to humans, perhaps through other animals
Soon after the Chinese government acknowledged there was an outbreak of a mysterious new virus in late December in Wuhan, scientists raced to sequence its genome. By mid-January, they had it and shared it with the World Health Organization.
Soon after that, scientists saw that the virus closely resembled viruses that circulate in bats. “If you look at the genetic sequence of the virus, it’s closely related to a bat virus, about 96 percent the same,” Jim LeDuc, head of the Galveston National Laboratory, a level 4 biosafety lab in Texas, told Vox. “There’s been talk about a pangolin intermediate host; that’s probably not true.”
Chinese officials also reported that several of the first cluster of cases had ties to a live animal market where both seafood and other wildlife were sold as food. (The market has since been closed.) The market soon became the leading hypothesis for how the virus made the leap into humans, where it’s been able to spread efficiently ever since.
The genetic evidence and epidemiological information, according to three esteemed infectious disease researchers writing in the New England Journal of Medicine, “implicates a bat-origin virus infecting unidentified animal species sold in China’s live-animal markets.”
“The widespread hypothesis that the first person was infected at an animal market in November is still plausible,” Stadler said in a statement. “Our data effectively rule out the scenario that the virus circulated in humans for a long time before that.”
In other words, nature came up with these weird characteristics in the genome, either in an intermediary animal between bats and people or in humans after the virus infected one. As Racaniello put it on his podcast: “Humans could never have dreamed this up.”
originally posted by: and14263
At first I was irritated by the speed at which a law suit has been filed against China. Typical litigation behaviour upon which America is built, not so easily accepted by other regions; this suing culture is growing of course, to the detriment of society.
But then I read a little further into the paperwork:
"Furthermore, there are only two known Chinese government bio-weapon research labs in the PRC and one of them — the National Biosafety Laboratory at the Wuhan Institute of Virology — is, at its name suggests, in Wuhan, and is close in proximity to the marketplace where COVID-19 allegedly originated. It is considered China’s only “level 4” microbiology lab – meaning it deals with the deadliest of viruses. An alternative theory here is that COVID-19 escaped from the Wuhan lab because of lax controls, or that Chinese researchers sold lab animals to the marketplace in question, as researchers have been known to do in China, instead of cremating them as PRC law requires. In either case, such conduct, as an alternative theory, has caused the pandemic."
This law suit is openly discussing the conspiracy we have known about for months.
Charles Lieber, the chair of Harvard University's Department of Chemistry and Chemical Biology, has been arrested and criminally charged with making "false, fictitious and fraudulent statements" to the U.S. Defense Department about his ties to a Chinese government program to recruit foreign scientists and researchers.
The Justice Department says Lieber, 60, lied about his contact with the Chinese program known as the Thousand Talents Plan, which the U.S. has previously flagged as a serious intelligence concern. He also is accused of lying about about a lucrative contract he signed with China's Wuhan University of Technology.
In an affidavit unsealed Tuesday, FBI Special Agent Robert Plumb said Lieber, who led a Harvard research group focusing on nanoscience, had established a research lab at the Wuhan university — apparently unbeknownst to Harvard.
In response to the charges against Lieber, Harvard said in a statement to NPR: "The charges brought by the U.S. government against Professor Lieber are extremely serious. Harvard is cooperating with federal authorities, including the National Institutes of Health, and is initiating its own review of the alleged misconduct. Professor Lieber has been placed on indefinite administrative leave."