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Sometimes to help the body, you have to fool the body, which is why researchers from Harvard's Wyss Institute of Biologically Inspired Engineering modeled their latest DNA nanodevice after those great immune-system evaders, viruses.
The solution was to model the DNA bots after something that had more experience fooling the immune system. So the white blood cell-inspired DNA nanodevices got a virus-inspired cloaking device. They enclosed the nanodevices in a solid protein case. The researchers then made tiny DNA handles upon which they could hang lipids to create an oily coating like the kind that viruses use to evade the immune system.The result was a very virus-like DNAbot.
BEIJING: Chinese scientists said they have successfully created and tested the world’s first autonomous DNA nanorobots to combat cancer tumors, paving the way for revolutionary cancer therapy. Scientists from China’s National Center for Nanoscience and Technology (NCNST) led the research and cooperated with scientists from Arizona State University in upgrading the design of the nanorobots. The scientific study was published in Nature Biotechnology in February.
According to researcher Ding Baoquan, the DNA-based nanorobot has a tube-shaped structure with a diameter of about 19 nanometers and a length of about 90 nanometers. “The nanorobot is exceptionally small and impossible to see with naked eyes. It is about 5,000 times smaller than the tip of a needle,” Ding said.
According to scientist Zhao Yuliang, the research team also conducted extensive safety studies of the nanorobots in two different mammals, including the Bama miniature pig, which is physiologically and anatomically similar to humans.
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