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Phylogenetic analysis showed that bat-derived coronaviruses fell within all five subgenera of the genus Betacoronavirus. Moreover, bat-derived coronaviruses fell in basal positions in the subgenus Sarbecovirus, with 2019-nCoV most closely related to bat-SL-CoVZC45 and bat-SL-CoVZXC21, which were also sampled from bats.23 These data are consistent with a bat reservoir for coronaviruses in general and for 2019-nCoV in particular.
Therefore, on the basis of current data, it seems likely that the 2019-nCoV causing the Wuhan outbreak might also be initially hosted by bats, and might have been transmitted to humans via currently unknown wild animal(s) sold at the Huanan seafood market.
More generally, the disease outbreak linked to 2019-nCoV again highlights the hidden virus reservoir in wild animals and their potential to occasionall spill over into human populations.
Beijing’s crackdown on civil society, freedom of expression made it impossible for people to raise the alarm about the situation, Tsinghua University professor Xu Zhangrun says in online article
Intellectual Xu Zhiyong repeats his call for ‘not very smart’ Xi to step down as leader
Despite his presence on social media, Xu Zhiyong has been in hiding from the police since December, following a year-long crackdown targeting civil rights dissidents that saw many people accused of inciting state subversion and detained.
originally posted by: liejunkie01
originally posted by: musicismagic
originally posted by: liejunkie01
a reply to: ShortBus
Is it wrong to prep? Nope. Is it wrong to inform those around you about the potential? Nope.
But if EVERYONE did it right now, there would not be enough to go around and we don't need create a run on that stuff right now, but in 4 weeks when we really need too for the majority.
I just picked up another 25 pounds of rice, big container of hand sanitizer, and a case of paper towels after work earlier.
I am slowly picking up supplies because I believe that if this is not contained soon, then there will be empty shelves everywhere. I hope not, but just in case my family will be better off than most because I choose to think ahead a little.
I hope nothing comes from thus but, I have a pretty bad feeling that if I do not act a little on this, then it may be too late.
Good to be prepared, but you should add bottle water or at least know where you can at least get well water.
My greatest fear and this has not been brought up yet, is what about those working at the nuclear power plants. Can you imagine if they can't leave their homes?
I am currently contemplating more toilet paper.
Lol. I dont want to end up in a situation.
He notes the need for a quick, effective biological attack upon the U.S. to depopulate it as a prelude to conquest, and plainly states that China is working on genetic bio-weapons to kill everyone except "yellow people."
originally posted by: dontneedaname
Mods should consider making a separate 2019-nCoV forum. Threads like this...individual stories get easily lost and buried, seen only by a few. Separate space would be easier to classify stories.
originally posted by: liejunkie01
Another possible case here in Illinois. Getting closer to home folks.
CHAMPAIGN, Ill. (WAND) – A possible case of the coronavirus could be in Champaign County. However, the Champaign-Urbana Public Health district hasn’t confirmed the information.
Illinois Radio Network said on Tuesday that a child in the C-U area is suspected of having the virus.
possible case
I am currently getting a little nervous here.
Wtf
originally posted by: liejunkie01
originally posted by: hopenotfeariswhatweneed
a reply to: liejunkie01
Anyone in the U.S died yet from this virus as far as you know ?
Did anyone ever hear anything about the 1,200 people in quarantine at the military bases?
In this study, we investigated the receptor usage of the SL-CoV S by combining a human immunodeficiency virus-based pseudovirus system with cell lines expressing the ACE2 molecules of human, civet, or horseshoe bat. In addition to full-length S of SL-CoV and SARS-CoV, a series of S chimeras was constructed by inserting different sequences of the SARS-CoV S into the SL-CoV S backbone. Several important observations were made from this study. First, the SL-CoV S was unable to use any of the three ACE2 molecules as its receptor. Second, the SARS-CoV S failed to enter cells expressing the bat ACE2. Third, the chimeric S covering the previously defined receptor-binding domain gained its ability to enter cells via human ACE2, albeit with different efficiencies for different constructs. Fourth, a minimal insert region (amino acids 310 to 518) was found to be sufficient to convert the SL-CoV S from non-ACE2 binding to human ACE2 binding, indicating that the SL-CoV S is largely compatible with SARS-CoV S protein both in structure and in function.
originally posted by: misfit312
a reply to: weirdguy
Thank you! I was looking for this and couldn't find it. May I ask do you have your own theory on what the "mystery" middle part is? Or a theory about the 2 virus that might have combined to make this virus?
PS I'm not asking to share your theory just if you have one.
originally posted by: slatesteam
a reply to: weirdguy
All I heard is you ain’t quite a virologist