Cancer = Immune System Disease: Tel Aviv ~ novel NANO-VACCINE for melanoma

Check out this cool news from Tel Aviv researchers! I heard something about this a while ago, and it was being rubbished by the biased, non-scientific & basically uneducated media types. Well they sure screwed up there - this research is now published in the journal 'Nature Nanotechnology'.

They have introduced a flurry of nanoparticles (170 Nm diameter) into mice, with the particles containing two peptide chains identical to those found on the surface of melanoma cells, which basically stimulates the immune system to attack & destroy the melanoma cells.

The big secret about cancer, which people aren't told (at least not in the UK) is that cancer is an immune system disease, and we are therefore underinformed to a huge degree that by taking actions which support the immune system - we are able to mitigate the worst effects of the cancer, or even to ensure that we overcome it completely. This includes exercise, it includes the right diet (with plenty of the 'superfoods' which are known to support the immune system), and - very important - activities such as meditation, hypnotherapy, or talk therapy - all of which lowers the production of stress hormones such as cortisol. Cortisol literally switches off the immune response, because the stress is perceived by the immune system to be an indicator that 'worse problems may be up ahead', and thus it minimises its own activities, counterintuitively guarding against possible future threats, even to the extent of ignoring the clear & present danger of a cancerous invasion in the body.

If we were to eat all the right foods, and to exercise (stimulating pleasure hormones such as oxytosin & serotonin, dopamine (etc)), and if we were to actively reduce our stress by positive relaxation exercises as described above, then we actually activate the so-called 'placebo effect' (which should be renamed as the 'natural intensive healing response' , derived from our immune & other related systems).

The so-called placebo effect is thought to be actively responsible for up to a third of all medical healings, period, throughout the world - acrosss all cultures; involving access to widely varying standards of medical care. Ironically, the so-called placebo effect is unleashed only when we feel we are being looked after, having our condition investigated by competent persons, that care arrangements or social support is in place where necessary, and so on. If we feel we are being cared for our production of pleasure hormones outweighs the stress hormones, meaning that we are naturally geared towards feeling better - but it's deeper than that alone. Our immune system always retains a measure of its potential healing energies as a reserve stock, and only when we feel that we are safe, receiving competent care & investigations (etc) can the system release all available energies for the healing process. If we do not feel safe, if we are uncertain about our care, if we are still producing stress hormones in large quantities, then our immune system responds to the presence of those hormones by witholding its energies sor the express purpose of the need to guard against future probelms - holding a reserve stock of energy & action in order to ensure that we can weather the potentially stormy season we may be approaching. Of course the immune system isn't "thinking" per se, but it is responding to the chemical environment in fixed, immutable ways. If we are unwell (IE producing an immune response to counter a threat) and we are stressed, then the response to those stress hormones is to minimise the active expenditure of energy & cellular capabilities which is current, so as to retain a potential for countering perceived likely future threats. If we are calm & relaxed, but still mounting an immune response - our immune system responds fully to the immediate health concern, because a lack of stress hormones suggests an external environment which is stable & unlikely to require a reserve of energies & cellular capabilities to be unleashed in response to 'imagined' future threats.

So yeah - stay chilled, trust your doctors, take the tablets, eat well, exercise a little, do enjoyable things with family & friends - and you will likely weather the storm of a current illness far better than if you become stressed & agitated & cut down on enjoyable pastimes (even just social contact can help).

Back to the main topic of the thread:

From Source

Researchers at Tel Aviv University have developed a novel nano-vaccine for melanoma, the most aggressive type of skin cancer. Their innovative approach has so far proven effective in preventing the development of melanoma in mouse models and in treating primary tumors and metastases that result from melanoma.

The focus of the research is on a nanoparticle that serves as the basis for the new vaccine. The study was led by Prof. Ronit Satchi-Fainaro, chair of the Department of Physiology and Pharmacology and head of the Laboratory for Cancer Research and Nanomedicine at TAU's Sackler Faculty of Medicine, and Prof. Helena Florindo of the University of Lisbon while on sabbatical at the Satchi-Fainaro lab at TAU; it was conducted by Dr. Anna Scomparin of Prof. Satchi-Fainaro's TAU lab and postdoctoral fellow Dr. João Conniot. The results were published on August 5 in Nature Nanotechnology.

Melanoma develops in the skin cells that produce melanin or skin pigment. "The war against cancer in general, and melanoma in particular, has advanced over the years through a variety of treatment modalities, such as chemotherapy, radiation therapy and immunotherapy; but the vaccine approach, which has proven so effective against various viral diseases, has not materialized yet against cancer," says Prof. Satchi-Fainaro. "In our study, we have shown for the first time that it is possible to produce an effective nano-vaccine against melanoma and to sensitize the immune system to immunotherapies."

'FOR THE FIRST TIME"... Darn right - this is a big deal! It really seems that the Israelis are going for broke in an area of research which has been largely quashed or rubbished by the Big Pharma stooges who want for everyone to be on a chemotherapy drip, and the medical establishment which has a somewhat vested interest (and may be over a barrel anyway, beholden to Big Pharma just like we are).

Can someone fistbump Israel for this? Assuming you're not all safe space screeching pansies who equate Israel with the words "[A]buse of the poor, fragile Muslims..." - supporters of Antifa & haters of Trump..

If you're sane & normal, this is exciting news, and heralds a new dawn in the diagnosis & treatment of all cancers.

Nanotechnology is coming into its own...

"And God saw that it was Good"..!!

Continued.....

From Source

The researchers harnessed tiny particles, about 170 nanometers in size, made of a biodegradable polymer. Within each particle, they "packed" two peptides -- short chains of amino acids, which are expressed in melanoma cells. They then injected the nanoparticles (or "nano-vaccines") into a mouse model bearing melanoma.

"The nanoparticles acted just like known vaccines for viral-borne diseases," Prof. Satchi-Fainaro explains. "They stimulated the immune system of the mice, and the immune cells learned to identify and attack cells containing the two peptides -- that is, the melanoma cells. This meant that, from now on, the immune system of the immunized mice will attack melanoma cells if and when they appear in the body."

ETA - Astonishingly simple!

The researchers then examined the effectiveness of the vaccine under three different conditions.

First, the vaccine proved to have prophylactic effects. The vaccine was injected into healthy mice, and an injection of melanoma cells followed. "The result was that the mice did not get sick, meaning that the vaccine prevented the disease," says Prof. Satchi-Fainaro.

ETA - Whaaaaaaaaaat? A literal vaccine against CANCER??? This is freaking awesome - shout it from the hilltops..!!

Second, the nanoparticle was used to treat a primary tumor: A combination of the innovative vaccine and immunotherapy treatments was tested on melanoma model mice. The synergistic treatment significantly delayed the progression of the disease and greatly extended the lives of all treated mice.

ETA - This is remarkable, and everyone should be getting on board with this approach. Tell your Congressman/ Minister of Parliament..!!

Finally, the pb[researchers validated their approach on tissues taken from patients with melanoma brain metastases. This suggested that the nano-vaccine can be used to treat brain metastases as well. Mouse models with late-stage melanoma brain metastases had already been established following excision of the primary melanoma lesion, mimicking the clinical setting. Research on image-guided surgery of primary melanoma using smart probes was published last year by Prof. Satchi-Fainaro's lab.

"Our research opens the door to a completely new approach -- the vaccine approach -- for effective treatment of melanoma, even in the most advanced stages of the disease," concludes Prof. Satchi-Fainaro. "We believe that our platform may also be suitable for other types of cancer and that our work is a solid foundation for the development of other cancer nano-vaccines."

What more needs to be said? Like Trump, I'm endearingly running out of superlatives to describe how wonderful this news truly is. A new dawn for cancer TREATMENT, validated according to reasonable recreations of real-world conditions. Please share this information, and read from the source, there is more information there.

Cheers, FITO.

a reply to: FlyInTheOintment

Cancer is not an immune system disease. I don't know why you think people trash this treatment. It's been used a long time.

Very cool!
Thanks for bringing this to our attentions.
Very well thought out.
I didn't realise how wide spread the placebo effect is.--- do you have any source I can look Into for more information on that?

a reply to: SupermassiveBlackHOLE

about the placebo effect...studies show the more you pay for something the better the placebo will work ( mentally we think this is expensive so it must be really powerfull and will work really well)

It is probably acting like Chaga Mushrooms that stimulate the body to fight certain kinds of cancer while being filled with lots of antioxidants to help slow cancer growth. There are multiple ways to help keep our body ready and active for killing cancer cells as they form. None of these include junk foods.

Lots of foods help us fight cancer, you just have to eat them once in a while.

a reply to: rickymouse

what other foods do we have to eat?

originally posted by: dantanna
a reply to: rickymouse

what other foods do we have to eat?

Celery helps promote apoptosis of rapidly dividing cells. The leaves are the most potent part of that plant. It contains apigenin and lutinen in high amounts, and parsley is actually way higher than celery. Oregano also contains this chemistry, actually all of the parsley family does. Now the lower part of these plants contains eugenol, the celerian root is high in that. It is related but can cause some very bad side effects for some people. Narangeenan in grapefruit possesses this quality as does quercetin in onions.

Then you can take rutabagga, the cruciferous veggies have a chemistry that reduces the ability to grow, but the form of caffeic acid in rutabagga is very anticancer. Soup made from organic beef bones and cartilage is also anticancer. With non-organic commercial grain fed beef, the glycine in the cartilage is replaced somewhat with an organic phosphate bound to glycine.....Glyphosate. So that does not work as well as real natural beef cartilage. It is the amount of the glyphosate they treat the grains with for decification that increases the content in the cartilage. It also goes into the collegen that marbles the rib steaks of the meat and we absorb more and it can cause inflammation in our joints and can cause brittle joints. I have read so much on that subject that I now try to buy organic grains because they do not preharvest treat these with roundup.

The problem with the other cruciferous veggies is that because they are goitrogens they also suppress the thyroid which lowers our immune systems ability to fight the cancer. Moderate consumption occasionally does not seem to be a problem, but eating them too often is not good, same goes with overconsumption of rutabagga. Radishes also have this compound that rutabaggas do.

Our immune system needs to properly communicate with the brain, consuming acetylcholine dampening chemistry regularly can lead to our body not identifying the cancer or pathogens and processing them properly. Betaine is a similar plant based chemical that helps in the brain, but too much Betaine is not good either,

Getting cancer is a multistep process, we have safeguards built in to trigger our body to destroy mutated cells. If you mess up one or two of the six or so steps, the body will still fix the issue. Now look at how many people have cancers, meaning that all the steps are messed up. You can have five of the six or more steps messed up and probably will not get cancer. in other words, we are consuming all kinds of bad cancer, note that they listed Roundup as a possible carcinogen, that it contributes to cancer. That is because it destroys a few anticancer pathways, one being it kills some microbes that we need to help to process some carcinogenic chemistry. The other is because of the glycine mess that can cause problems in the bones, it mutates the blood making cells in the bones and also increases inflammation all over our body in the joints, our body is spending it's time fighting things that it shouldn't be fighting, depleting it's immune system and it also does not see the cancer cells till to late.

Roundup is not causing cancer on it's own though, there are multiple pathways being disrupted because of improper food chemistry being combined, also there are chemicals we breath in from our environment and stuff we put on our skin that can be absorbed. Triclosan actually alters a pathway that glyphosate does which increases our cancer risk. That is quickly absorbed in our skin.

I get this information from reading scientific journal articles that anyone can actually read if they want. It took me about ten years of monitoring research about the metabolic pathways involved in glyphosate to adopt a stance against eating it on a daily basis. Our bodies can detox this chemical a little, but with using it to decicate the crops of grains preharvest, it raises the levels to too high a level for people to detox. This is probably why those who give up gluten and do the paleo and keto diets seem to benefit so much. They are reducing grain consumption, grain decicated with glyphosate or related chemistries. So their inflammation goes away.

Until this year, I was neutral on glyphosate, knowing for five years that it was used to decicate grains. It's metabolite is almost as dangerous as the chemical itself is too, when broken down it is still a problem much of the time. I now use organic flour and feel much better, it is organic white whole wheat, but I have tried the non whole wheat version too, it is about the same, it does not bother me. I am not gluten intolerant because I still eat the same, only the flour being organic has changed.