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In Morocco there grows a cactus-like plant that’s so hot, I have to insist that the next few sentences aren’t hyperbole. On the Scoville Scale of hotness, its active ingredient, resiniferatoxin, clocks in at 16 billion units. That’s 10,000 times hotter than the Carolina reaper, the world’s hottest pepper, and 45,000 times hotter than the hottest of habaneros, and 4.5 million times hotter than a piddling little jalapeno.
But while that toxicity will lay up any mammal dumb enough to chew on the resin spurge, resiniferatoxin has also emerged as a promising painkiller. Inject RTX, as it’s known, into an aching joint, and it’ll actually destroy the nerve endings that signal pain. Which means medicine could soon get a new tool to help free us from the grasp of opioids.
Yep when you have a tooth ache no drug is off limits.
originally posted by: Allaroundyou
a reply to: Fowlerstoad
If someone has the urge to not use drugs then ya good idea. But a lot of people take those pills to get high.
The only time I allow myself to take one of those pills is for tooth pain. Cause that shiz sucks.
Cool find either way!
Volume 60, Issue 10, 31 January 1997, Pages 681-696
Euphorbium: Modern research on its active principle, resiniferatoxin, revives an ancient medicine.
Though resiniferatoxin was isolated only two decades ago, the dried latex of Euphorbia resinifera, called Euphorbium, has been in medicinal use since the time of recorded history. This review highlights the most important events in the history of this ancient medicine, from the first written record of the therapeutic potential of Euphorbium (at the time of the reign of the Roman Emperor Augustus) to the identification of its active principle as resiniferatoxin in 1975. 44
Does this mean the patient will feel extreme pain in those nerves until they're deactivated? Kinda sounds like it.
originally posted by: RealityIsAbsurd
a reply to: peskyhumans
From the same article:
When RTX binds to TRPV1, it props open the nerve cell’s ion channel, letting a whole lot of calcium in. That’s toxic, leading to the inactivation of the pain-sensing nerve endings.