.
.
.
FYI - A few articles to consider re: the appearance of this new form of AIDS.
[
Note: Infectious prions are proteins - and capable of infecting viruses, bacteria and other microbes, not just animals.]
This 1986 paper describes how "proteinaceous capsids" (prions) use viruses as vehicles of transmission...
* "Viral influences on aflatoxin formation by Aspergillus flavus." Appl Microbiol Biotechnol 24:248-252. Schmidt FR, Lemke PA, Esser K (1986)
"Epidemiological observations indicate that a microbial vector is responsible for the transmission of natural prion disease in sheep and goats …
...It is proposed that many microbial proteins may be capable of replicating themselves in mammalian cells eliciting and sustaining thereby
degenerative and/or autoimmune reactions subsequent to infections with microorganisms."
* Med Hypotheses. 1999 Aug;53(2):91-102. Is the pathogen of prion disease a microbial protein? Fuzi M. Budapest Institute of National Public Health
and Medical Officer Service, Hungary. PMID: 10532698
* Dangerous liaisons between a microbe and the prion protein. J Exp Med. 2003 Jul 7;198(1):1-4. Aguzzi A, Hardt WD. PMID: 12847133
The Spongifrom Encephalopathy (SE) is a lesion, described for the human beings in the Creutzfeldt Jacob disease (CJD), the
Gerstmann-Straüssler-Scheinker syndrome, the fatal familial insomnia, the Kuru, and for the animals, particularly in the frame of the epidemy of
Bovine Spongiform Encephalopathy (BSE), responsible for the actual crisis of mad cow. The pathologic form of prion (mutated form) would be the causal
agent of these SE (SB. Prusiner, 1981). Other authors (L. Manuelidis, 1995) have suggested that a retrovirus (not yet identified) could intervene as a
causal agent.
SE lesions have been described on histological sections from the brain of a patient suffering from AIDS dementia (J. Schwenk, 1987). These lesions
have been since described (J. Artigas, 1989) for 5 other HIV+ patients. However, a publication recently reported 67 cases of SE on 200 autopsies of
patients dead of AIDS (AJ Martinez et coll., Path. Res. Pract. 191, 427-443, 1995).
This lesion appears not to be an epiphenomenon, but maybe a major component of AIDS.
Mad Cow Lesions in AIDS
"According to a study from France, "...the human PrPc was shown to possess nucleic acid binding and chaperoning properties similar to human
immunodeficiency virus type 1 (HIV-1) nucleocapsid protein, a key viral factor in virus structure and replication. These findings prompted us to
determine if PrPc could influence HIV-1 replication." "
J Mol Biol. 2004 Apr 2;337(4):1035-51. "Analysis of the interactions between HIV-1 and the cellular prion protein in a human cell line"
[S52.008] Detection of Prion Amyloid Deposits In Vivo
Category - Infections/AIDS/Prion diseases
Barring the door to HIV: The prion propagates Host-virus battle
(This article available free to registered subscribers)
.