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[Researchers] have developed a portable, thumbnail-sized silicon chip that can, in a fraction of a second, reprogram skin cells so that they transform into just about any other cell type in the body. The noninvasive tissue nanotransfection (TNT) technology has already been used in mice and pigs to prompt skin cells to develop into complete blood vessels that join up with existing vasculature to heal necrotizing skin flaps and to rescue critically injured ischemic legs. In subsequent experiments, TNT directed the transformation of mouse epidermal skin cells into functioning neurons that within just a few weeks could be removed from the skin layer and transplanted into the animals’ brains to reverse the effects of a stroke.
This is difficult to imagine, but it is achievable, successfully working about 98 percent of the time. With this technology, we can convert skin cells into elements of any organ with just one touch. This process only takes less than a second and is non-invasive, and then you're off. The chip does not stay with you, and the reprogramming of the cell starts. Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary," said Sen, who also is executive director of Ohio State's Comprehensive Wound Center.
Alternatively, a patient’s skin can be considered as an ‘agricultural landscape’ for growing and harvesting therapeutic cell types for implantation elsewhere in the body. We have, for example, generated hundreds of thousands of neurons in the skin of mice. It takes just 3-4 weeks for functional neurons to be ready for grafting into the brain.”
“We are quite surprised that the transfection is able to propagate into the deeper layers of skin tissue cells,” Dr. Lee admitted to GEN. “Our current results show that the transfected surface cells are able to release functional biomolecules, including mRNA and proteins, some in secreted extracellular vesicles, to relay the transfection to other cells in the tissue.”
originally posted by: worldstarcountry
Can it be used to grow existing tissue making it larger
Oh yes, you know exactly where I am going with this