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Unexpected new lung function discovered: Making blood
Our bodies still hold plenty of secrets, and scientists have just uncovered a doozy: the lungs play a key role in producing blood. Until now, this task was ascribed solely to bone marrow, but studies on mice at the University of California San Francisco (UCSF) have found that, surprisingly, the majority of the body's platelets are produced in the lungs, as is a backup reservoir of blood stem cells that can step in when those in the bone marrow run dry.
...the megakaryocytes in the lungs were creating more than 10 million platelets an hour, constituting more than half of a mouse's total amount. That population appears to be fed by a group of megakaryocyte progenitor cells and blood stem cells that are living just outside the main lung vasculature. The team spotted these cells – numbering at around a million per lung – with video microscopy techniques.
..."This finding definitely suggests a more sophisticated view of the lungs – that they're not just for respiration, but also a key partner in formation of crucial aspects of the blood," says Mark R. Looney, MD, senior author of the study. "What we've observed here in mice strongly suggests the lung may play a key role in blood formation in humans as well."
While the lungs may appear to be doing much of the work, bone marrow is no slouch. In fact, the two seem to work together to make blood.
..."It's fascinating that megakaryocytes travel all the way from the bone marrow to the lungs to produce platelets," says Guadalupe Ortiz-Muñoz, co-first author of the study. "It's possible that the lung is an ideal bioreactor for platelet production because of the mechanical force of the blood, or perhaps because of some molecular signaling we don't yet know about."
originally posted by: Skywatcher2011
a reply to: soficrow
Cool...but why can't you change your title to say blood platelets????
originally posted by: anonfamily
Oh they knew... they just withheld the information.
The closer we get to knowing how everything works, the closer we get to being a threat.
Physics is in the same boat. We can't have masters of the matter walking around everywhere, better mislead them with an old theory from hundreds of years ago that still doesn't explain gravity...
originally posted by: dfnj2015
My brain first read the title of the thread incorrectly with "Lungs make butter". As in lung butter, grotesque.