a reply to: TzarChasm
Disappointingly, it seems I have lost the work (along with quite a bit more). I wasn't sure that I would bother posting it on ATS, but I wanted to
locate it either way.
I'm not too happy about it. That's a lot
of work just.. down the drain.
Well, some of the conclusions:
It didn't always affect individuals in the expected fashion. There was a surprising amount of diversity. Enough that it actually makes it quite
difficult to use as a medicine in some cases as well as proposing any overarcing legislation (like bringing it under the umbrella of DUI), at our
current state of knowledge. However, it was abundantly clear that in many cases, commonly held impacts (like driving ability) were more benign than
expected. In some cases, it had the opposite expected result.
The most important factor seemed to be the ratio of cannibinoids. Everything else was secondary, including consumption method and the typical
parameters (like THC or CBD content on its own).
There can be a significantly negative interaction between cannibis and narcotic pain meds. This, however, was actually that certain methods of
consumption and certain cannibinoid ratios can negate
the efficacy of the opioids. This also seemed connected to the cannibinoid ratios,
however, data is limited usually to just the major cannibinoids, making solid conclusions difficult.
Differences from batch to batch, even with the exact same strain, can yield massively differing efficacy. Taking a strain that has no negation effects
to one that does.
Importantly, cannabis is significantly less effective than
typical opiods in dealing with certain types of pain (bone pain for one), regardless
of ratios or consumption method. When combined with the effect of negation, this can lead to an entire day of greatly increased pain.
Consumption method can mitigate the negation, but not eliminate it.
There were more, but basically, my overall conclusions were that *all* cannibinoids play a major role and content of only one or two (high THC or high
CBD) is not as relevant as the ratios of all of the cannibinoids in play. Due to the lack of consistency inherent in a plant, it is difficult to truly
pin down the "right" amounts for a given treatment, even with great control over growth cycle, humidity, etc. And despite being an incredible option
for some, for others it can actually lead to a degradation in quality of life, due in large part to increased awareness of pain combined with negation
of current opioid medication (if present). Getting that last one even considered has been a fools errand.
I believe its also important to consider, in aspects like driving, the comparison between being "stoned" or being in great pain. In many cases, the
latter may result in much, much more distraction than the former. In some body chemistries with certain cannibinoid ratios, it not only managed the
distracting pain but improved
edit on 11-1-2017 by Serdgiam because: (no reason given)