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originally posted by: 5StarOracle
a reply to: [post=21048560]Barcs[ aroun/post]
That sounds good and all but it's the mutations that affect the copying... And that's not a good thing...
But what you said is false or at least rather misleading...
originally posted by: Noinden
a reply to: Phantom423
When one tries to grossly oversimplify a complex idea, one looses resolution. Your explanation is about as resolved as an 8bit picture.
originally posted by: Noinden
a reply to: 5StarOracle
They are the result of mutation. Mutation is a change in DNA, be it a single amino acid different, or be it several.
So yes, it is the result of what would be considered a replication error.
You are playing semantics in an area you don't know very well.
originally posted by: Noinden
a reply to: 5StarOracle
They are the result of mutation.
So yes, it is the result of what would be considered a replication error.
You are playing semantics in an area you don't know very well.
Mutation is a change in DNA, be it a single amino acid different,
originally posted by: Noinden
a reply to: Phantom423
You really can't read.
DNA, generally codes for proteins. Thus a mutation in DNA will usually result in different amino acids being made.
Look at Sickle Cell anemia. An A is changed to a T, in the area which codes for a glutamic acid, and replaces it with a valine. These are vastly different amino acids when it comes to properties.
So where am I getting this? Biochemistry. First year biochemistry in the commonwealth.
originally posted by: 5StarOracle
a reply to: Noinden
Around 5000 years ago a tolerance was gained by ingesting copious amounts of lactose...
Bacteria have gained a tolerance to antibiotics because of inept scientists...
Those are not examples for replication errors in DNA though are they?
Lactase nonpersistence is the ancestral state, and lactase persistence only became advantageous after the invention of agriculture, when milk from domesticated animals became available for adults to drink. As expected, lactase persistence is strongly correlated with the dairying history of the population. This genetic ability to digest milk has been regarded as a classic example of gene-culture co-evolution, where the culture of dairying creates a strong selective advantage to those who can drink milk as adults, for only they can nutritionally benefit from the milk. A recent paper confirmed this link by analysing the diversity in bovine milk protein genes and showing that the highest gene diversity (and by implication the largest historical population size) is in cows from areas of the world where dairy farming is practised and the people are lactose tolerant.2 In humans, epidemiological analysis has shown that the cultural development of dairying preceded selection for lactase persistence.3 Since dairying is thought to have originated around 10 000 years ago, the selective pressure has been only for the past 400 generations. Despite this short time, there is suggestive evidence of recent positive selection: lactase persistence is associated with one haplotype, which is very common only in northern Europeans, and is distant from the ancestral haplotype.4, 5 Discovery of the possible molecular basis of this polymorphism – a single nucleotide change 14 kb away from the gene, has allowed further analysis of genetic variation associated with lactase persistence/nonpersistence.6, 7, 8
originally posted by: Noinden
So yes, it is the result of what would be considered a replication error.