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The thalamus (from Greek θάλαμος, "chamber")[1] is a midline symmetrical structure of two halves, within the vertebrate brain, situated between the cerebral cortex and the midbrain. Some of its functions are the relaying of sensory and motor signals to the cerebral cortex,[2][3] and the regulation of consciousness, sleep, and alertness.
The interthalamic adhesion (also known as the mass intermedia or middle commissure) is a flattened band of tissue that connects both parts of the thalamus at their medial surfaces. The medial surfaces form the upper part of the lateral wall to the third ventricle.
In mammals other than humans, it is a large structure. In humans it is only about one centimetre long, though In females it is larger by about 50%.[1]Sometimes it is in two parts and 20% to 30% of the time it is absent.
Absence of the interthalamic adhesion may be associated
with schizophrenia. Crippa et al. have reported absence
of interthalamic adhesion in 18.42% of schizophrenic
individuals and in 10.53% or normal individuals [5]. In
another study by Meisenzahl et al. it was absent in 23.3%
of schizophrenic population and in 13.3% of normal
population
The existence of an interthalamic adhesion (in 70% of brains) might alter the flexibility of the third ventricle, as the tissue of the IA would be less pliant, and might restrict movement, compared to an open fluid-filled space capable of more expansion, present in only 30% of human brains without an interthalamic adhesion.
The subtle pulsatile motion of the Cranial Rhythm is body-wide and includes slow rhythmic changes to the shape and volume of the third cranial ventricle in the midline, at the centre of the head, swelling with expansion and deflating with contraction.
CRI motion occurring in this evolutionarily ancient area of the brain, where mechanical, fluid, neural and hormonal functions all overlap, has a pivotal homeostatic role.
A client who has a third ventricle without an interthalamic adhesion could be capable of greater cranial rhythm amplitude (the range between expansion and contraction) than a client with it present.