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Ayahuasca (UK /ˌaɪjəˈwæskə/; US /ˌaɪjəˈwɑːskə/), also commonly called yagé (/jɑːˈheɪ/ or /jæˈheɪ/), is an entheogenic brew made out of Banisteriopsis caapi vine and the Psychotria viridis leaf. The brew is used as a traditional spiritual medicine in ceremonies among the Indigenous peoples of Amazonian Peru, many of whom say that they received the instructions in its use directly from the plants and plant spirits themselves.