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The victims were buried when a vast heap of waste material, discarded by the mining companies, collapsed in Kachin state, Burmese media reported.
Many of the dead were scavengers living on or near the waste dumps, who search through the debris in the hope of finding fragments of jade to sell.
advocacy group Global Witness said that the value of jade produced in 2014 alone was $31bn (£20.4bn) - the equivalent of nearly half the country's GDP - yet hardly any of the money is reaching ordinary people or state coffers.
Local people in mining areas accuse the mining industry of a series of abuses, including poor on-site health and safety and frequent land confiscations.
Many jade mining areas have been turned into a moon-like areas of environmental destruction as huge diggers churn the earth in search of the translucent green stones.