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Egypt-born Sharif won two Golden Globe awards and an Oscar nomination for his role as Sherif Ali in David Lean's 1962 epic Lawrence of Arabia.
He won a further Golden Globe three years later for Doctor Zhivago.
Earlier this year, his agent confirmed that he had been diagnosed with Alzheimer's disease.
His agent Steve Kenis said: "He suffered a heart attack this afternoon in a hospital in Cairo."
www.bbc.co.uk...