posted on May, 9 2015 @ 08:04 PM
a reply to: swanne
Don't get me wrong, the research into how methylated bases impact expression is fascinating, but this is hardly the first "official"* base added to
the mix. A, C, G, T, and U are commonly referred to as "primary bases". There quite a few modified bases out there, including:
mA, mC, mG from methylation of their respective counterparts
Pseudouridine is an isomer of uridine
dHU from hydrogenation of uridine
Xanthene and hypoxanthene from deamination of G and A, respectively
That's an even dozen bases right there, and I'm pretty sure there are more than that.
* Can you explain why you think it's suddenly "official" now as opposed to when it was first identified?