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Anoxic regeneration of NADH is only an effective means of energy production during short, intense exercise, providing energy for a period ranging from 10 seconds to 2 minutes and is dominant from about 10–30 seconds during a maximal effort. It replenishes very quickly over this period and produces 2 ATP molecules per glucose molecule, or about 5% of glucose's energy potential (38 ATP molecules in bacteria). The speed at which ATP is produced is about 100 times that of oxidative phosphorylation. The pH in the cytoplasm quickly drops when hydrogen ions accumulate in the muscle, eventually inhibiting enzymes involved in glycolysis.