posted on Oct, 15 2014 @ 06:39 PM
a reply to: new_here
Getting the antibodies out of the blood is probably not the hard part. It is kinda a chicken or egg situation. First, you need to isolate an antigen
on the Ebola virus. Your first step is to have antibodies or portions of antibodies that are set on an array or chip connect to the antigen on the
Ebola virus. Note antigens are the molecules that antibodies bind to on the virus or bacteria or some other foreign invader.
Once you have captured the Ebola virus then you would snip the specific antigen away from the rest of the virus. Probably done by some type of
restriction enzyme. Then make the antibody that "caught" the antigen release the antigen. Tag the antigen with something like a probe or marker that
will allow you to easily separate out the antigen after it has bound to the antibody that was in the blood of a previously infected individual.
Now the hard part. Separate the antigen from the antibody without affecting the functionality of the antibody. If you can do that, you will have
'extracted' the antibody from the blood. Repeating, the hard part is keeping the antibody's functionality not isolating the antibody.
I do not know how the rabies shots work. I would have to look it up to understand the process. Sorry.
I looked up rabies treatment. The treatment is to vaccinate the individual with inactive form of the rabies virus. This works because the rabies
virus has a long incubation time before becoming infectious. The shots are repeated to keep your own antibodies level high until after rabies virus
incubation period has ended. After a while your body would normally stop producing the antibodies because your body would consider that unnecessary
and wasteful. If you get a second infection, then your body would go to the next level and be ready to produce antibodies at a moments notice. That
is the basic premise of vaccination. You get an initial infection with either an inactivated form, a close relative like cowpokes for chicken pox or
you are given only an antigen snippet without the whole virus or bacteria. This will cause your body's initial immune system response. Once you get
a real infection your body will then see that as a second infection and respond accordingly.
edit on 15-10-2014 by feldercarb because: (no
edit on 15-10-2014 by feldercarb because:
Note: Forgot to say that there are multiple antigens on the Ebola virus. You need to find the antigen that the "killing" antibody binds to. Thus
when you use the antibody chip or array, you may get multiple antigens to bind. You then have to individually test each captured antigen vs the blood
to get the antibodies and you will also need to test which antibody is the most effective antibody. More than one antibody may work.
15-10-2014 by feldercarb because: Added note