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ATLANTA (CBS Atlanta/AP) — Dogs in one community in Liberia are reportedly eating the remains of dead Ebola victims lying on the streets.
The New Dawn reports that the Liberian government buried bodies of those suspected to have died from Ebola a few weeks ago in Johnsonville Township, outside of Monrovia. A number of dogs were reportedly seen pulling the bodies out of the graves and eating the remains.
Alfred Wiah tells The New Dawn that the government’s Health Ministry was called about the incident but that officials did not do anything about it.
Genetic studies of some of the earliest Ebola cases in Sierra Leone reveal more than 300 genetic changes in the virus as it leapt from person to person, changes that could blunt the effectiveness of diagnostic tests and experimental treatments now in development, researchers said on Thursday.
"We found the virus is doing what viruses do. It's mutating," said Pardis Sabeti of Harvard University and the Broad Institute, who led the massive study of samples from 78 people in Sierra Leone, all of whose infections could be traced to a faith healer whose claims of a cure attracted Ebola patients from Guinea, where the virus first took hold.
The findings, published in Science, suggest the virus is mutating quickly and in ways that could affect current diagnostics and future vaccines and treatments, such as GlaxoSmithKline's Ebola vaccine, which was just fast-tracked to begin clinical trials, or the antibody drug ZMapp, being developed by California biotech Mapp Biopharmaceutical.
originally posted by: loam
Anybody have any thought about this?
The World Health Organization says the past week has seen the highest increase of Ebola cases since the outbreak began, more evidence that the crisis is worsening.
originally posted by: jadedANDcynical
a reply to: loam
I'm eager to find what they're able to determine the mutations have added to the virus' pathogenicity. This aspect of what the virus is capable of has always been a great worry to me, and now we see why...
Senegalese Ebola patient evacuated to Germany for treatment
A WHO staffer who has contracted Ebola has arrived in Hamburg for treatment. The Senegalese epidemiologist is just one of many health workers who have contracted the deadly disease in West Africa.
The trade-off hypothesis suggests that there is a trade off between how long the virus or other pathogen is able to persist in its host and the rate at which the virus or other pathogen can be transmitted. The trade off hypothesis suggests that virulence will evolve to a level at which virulence and transmission is balanced so as to maximize the spread of the virus.
Viral lines with the higher enforced rate of infectious transmission evolved higher virulence and higher rates of virus production. These results support the trade-off model for the evolution of virulence.
The employee of Doctors Without Borders (MSF) quarantined in a Brussels hospital after suspected contamination Ebola, is the first real suspect case in Belgium, said Friday Sven Heyndrickx, spokesman for the Federal Public Health.
Thursday noon, the man fell ill while giving training to the association on the Tour & Taxis in Brussels. As he was returning from a risk area, it was immediately transferred to St. Peter's Hospital. "This man meets the three conditions of the high-risk category: it returns a hit by the disease, he was in personal contact with it and he has a fever," said Sven Heyndrickx.
If the man still has fever Friday a blood test will be performed. A definitive answer will be given at the earliest within two days, about a possible infection. Last week already, a Guinean 13 years had been quarantined in a hospital Ostend, but the youngster had actually contracted malaria.
Secretary of Health, Antoni Mateu, said the patient is a 38 year old Guinea suffered a head injury in Guinea Conakry, and could have been in contact with the virus.
Trauma care began in the Vall d'Hebron Hospital, but was transferred to the Hospital Clínic, where he was admitted to an isolation room for infectious diseases. Responsible area of Clinic Epidemiology noted that this patient has more symptoms than a previous case, but it is "unlikely" to give positive results.
For now, patient blood samples were sent to the National Microbiology Center Majadahonda (Madrid), according to the Coordination Center Health Alerts and Emergencies of the Ministry of Health, Social Services and Equality. The result of the analysis, which will be announced in the next 24 or 48 hours, determine the patient's diagnosis.
This is the second possible case of Ebola detected in Barcelona , after the Department reported last Friday of another potential patient, a Senegalese diplomat of 36 years finally gave negative. This August were activated similar protocols in Alicante and Bilbao, although both patients were negative to the Ebola virus . Moreover, religious Bohi Juliana who had come to Spain to be admitted to the Hospital Carlos III for possible case of Ebola was given high today, after 21 days of treatment, disease free.
Scientists have made a catalog of 345 mutations, which were placed in the public domain for all researchers, quoted by "Times" Science.
Current epidemic caused Zaire subtype of Ebola virus, the most dangerous. The specialists of the World Health Organization said that as long as the epidemic will be able to locate, the number of cases with Ebola can reach 20 thousand. persons . This is more than six times the number identified to date (3062) cases of infection. According to WHO, the Ebola outbreak in West Africa has claimed the lives of 1,552 people. In the recent epidemic is increasingly gaining momentum: more than 40% of cases have been recorded in the last three weeks.
Epidemiological modelling based on the data from previous EBOV outbreaks has produced a basic reproduction number (R0) of 2.7 with a 95% confidence range of 1.9 to 4.1 (Legrand et al., 2007). This R0 is comparable to influenza (Mills et al., 2004) and would seem to be comfortably within the range required to generate an EVD pandemic. In answer to the question of why this has not already occurred in human history, perhaps the most persuasive response is that EVD very fortunately only emerged into human populations around the time of its discovery in the mid-1970s (Walsh et al., 2005), by which time we were fairly equipped to deal with it in remote low population density settings. Whether we can contain it within a large city, should the necessity to do so arise, remains to be seen.
The best-fit estimates of the basic reproduction number are 1.52 for Guinea, 2.42 for Sierra Leone and 1.65 for Liberia. The model shows that control efforts in Guinea and Sierra Leone were successful in reducing the effective reproduction number below unity by the end of May and July 2014, respectively. In Liberia, however, the model estimates an effective reproduction number of around 1.5 in mid-August 2014. This suggests that control efforts in Liberia need to be improved substantially in order to stop the current outbreak.
Major pharmaceutical companies have shown little interest in developing effective treatments for diseases such as this. There’s no incentive for the commercial risks of research and companies naturally prefer to focus on diseases that can sustain large markets of wealthy regular users.
Let’s consider the most advanced drug: ZMapp, which is produced by Mapp Biopharmaceuticals and is the experimental treatment the fuss has been about. The incentive for developing ZMapp was clearly not its broad commercial potential. Instead, it is for developing capacity for biodefence.