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Size Of Human Genome Reduced To 19,000 Genes
A study led by Alfonso Valencia, Vice-Director of Basic Research at the Spanish National Cancer Research Centre (CNIO) and head of the Structural Computational Biology Group, and Michael Tress, researcher at the Group, updates the number of human genes –those that can generate proteins– to 19,000; 1,700 fewer than the genes in the most recent annotation, and well below the initial estimations of 100,000 genes. The work, published in the journal Human Molecular Genetics, concludes that almost all of these genes have ancestors prior to the appearance of primates 50 million years ago.
Scripps Research Institute Scientists Reveal How Deadly Ebola Virus Assembles
...the study showed that the same molecule that assembles and releases new viruses also rearranges itself into different shapes, with each shape controlling a different step of the virus’s life cycle.
“Like a ‘Transformer’, this protein of the Ebola virus adopts different shapes for different functions,” said Erica Ollmann Saphire, Ph.D., professor in the Department of Immunology and Microbial Science at TSRI. “It revises a central dogma of molecular biology—that a protein molecule has one shape that predestines one biological function."
…This “shape-shifting” or “transformer” behavior explains how the Ebola virus can control a multi-step viral lifecycle using only a very limited number of genes.
THE MYSTERIES: How can only 19,000 protein coding genes -shared by all humans- produce the absolute abundance of unique individual diversity called the human species? And - how can we share most of those genes with other animals and still be so different?
There are (excluding colour variations) currently 6448 different molds used in the production of Lego bricks
originally posted by: SonOfTheLawOfOne
Well, how different are we really?
....how different are we than any other species of creature...?
Over 99% of human protein coding genes have an origin that predates primates by over 50 million years.
THE MYSTERIES: How can only 19,000 protein coding genes -shared by all humans- produce the absolute abundance of unique individual diversity called the human species? And - how can we share most of those genes with other animals and still be so different? The latest research published in the journal Human Molecular Genetics finds that the number of human genes -those that can generate proteins- is 19,000. Not 20,700. Definitely not 100,000. Just 19,000. It also concludes, "almost all of these genes have ancestors prior to the appearance of primates 50 million years ago." How can that be?
originally posted by: soficrow
Of course, this means we all need to be very, very careful what we do to our personal, local and global environments - because our environmental exposures determine what happens to -and with- the proteins our genes produce, and how they function.
Why are you surprised by the conclusion of the study?