Stem Cell Research - your opinions, page 1
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reply posted on 30-11-2004 @ 10:40 PM by slank
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Another headline
Umbilical cord cells 'allow paralysed woman to walk
Headlines are used to sell papers,
people like miracles,
But stem cell research does almost sound like genuine biological fix-all putty.
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reply posted on 21-2-2005 @ 10:40 AM by soficrow
Originally posted by Thomas Crowne
WEll, my belief is if this was a really potential cure for any ails, the private sector would be in there like swimwear. Instead, a few are screaming that I pick up the tab.
A rat, I smellith!



I monitor what's happening in stem cell research because I have 3 incurable debilitating diseases. I am told that they are not related - yet each one of them is caused by mutated connective tissue stem cells.



My research suggests that stem cell therapies have been offered in exclusive private clinics since the early 1950's, at least. ...The technology appears to be very advanced, and has been modified and applied in the Genetically Modified Organisms (GMO) industry for example.

The reason stem cell therapies are not generally available is because the research and technologies are privately owned as Copyright and Intellectual Property Rights - the cost of licensing is prohibitive. ...It's called an "economic barrier."

...The current push for stem cell research seems mainly designed to bring the technology rights more into the public domain, and to make stem cell therapy accessible to everyone, not just the chosen elite.

...If you look to the right of this page you will see ads for stem cell therapies and cell therapies - they've been here since I first posted on stem cells 5 months ago. They do change, not sure what ads and links will be up when you look.

When I first researched stem cell therapy a few years ago, several international exclusive clinics were listed as stem cell therapy providers - the information posted was general, and prospective 'clients' had to provide a financial report to prove eligibility. As far as I can tell, people are offered access to levels of therapy within their "budget," if they qualify at all. ...My links no longer work. Probably shouldn't have posted them on the net.



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reply posted on 21-2-2005 @ 12:37 PM by soficrow
Originally posted by WolfofWar
Great thing about stem cells is now it can be taken from the umbilical cord, with no harm to the baby. ...The potentials for stem cells seem endless, and it seems to be the deffinitely progression in medical science. I don't see how anyone could appose it.




Scientists have been working with stem cells, including cord cells, for over 50 years in the public domain. Which means work in private clinics has been going on longer. The reason for using stem cells from different sources is that each kind has specific strengths and limitations.

The first and only stem cell transplant to become available to ordinary people is 'bone marrow' transplants for leukemia. The technology was developed in the 1950's and absolutely confirmed in the 1960's - but insurance companies did not want to cover it, so they claimed it was experimental. It took about 30 years of hard fighting to force insurance companies to acknowledge that transplanting stem cells from bone marrow to treat leukemia was NOT an experimental treatment.

...Here's a quick and dirty look at the public history of stem cell research.


1. Scientists have been working with umbilical cord stem cells, and others, for over 50 years.

Note: "Fibroblasts" are connective tissue stem cells.


* [Effect of human umbilical cord extracts on growth of in vitro culture of embryonal fibroblasts.] C R Hebd Seances Acad Sci. 1955 May 16;240(20):2018-20. LASFARGUES E, DANIEL P, DELAUNAY A. PMID: 14390784

* [Effects of human umbilical cord extracts on the growth of embryo fibroblasts cultured in vitro.] C R Hebd Seances Acad Sci. 1955 Jan 24;240(4):457-9. LASFARGUES E, DANIEL P, DELAUNAY A. PMID: 14364852

* Influence of human cord extracts on chick embryonic fibroblasts grown in vitro. Exp Cell Res. 1956 Feb;10(1):188-93. LASFARGUES EY, DELAUNAY A, DANIEL P. PMID: 13294127

* [Effect of human serum of benign tumor patients on fibroblasts cultivated in vitro.] Rev Soc Argent Biol. 1950 Apr-May;26(1-2):1-7. SACERDOTE de LUSTIG E, MANCINI RE. PMID: 14781570

* [Effect of human cerebrospinal fluid on the fibroblast in vitro.] Rev Soc Argent Biol. 1951 Jun-Jul;27(3-4):114-7. SACERDOTE DE LUSTIG E. PMID: 14900760

* Stimulating effect of nucleoprotein fraction of chick embryo extract on homologous heart fibroblasts.
Proc Soc Exp Biol Med. 1953 Jun;83(2):390-5. KUTSKY RJ. PMID: 13064279

* [Studies on growth promoting substances of embryonal extracts in fibroblasts cultures.] Biochem Z. 1953;324(3):195-203. BAYERLE H, BANDIER J. PMID: 13126131



2. Researchers have been transplanting stem cells for over 50 years.

* The development of variations in transplantability and morphology within a clone of mouse fibroblasts transformed to sarcoma-producing cells in vitro. J Natl Cancer Inst. 1954 Oct;15(2):215-37. SANFORD KK, LIKELY GD, EARLE WR. PMID: 13233880



3. The link between stem cell mutations and cancer was recognized over 50 years ago.

* [A case of stem-cell sarcoma of the reticular connective tissue of the endometrium.] Arch De Vecchi Anat Patol. 1956 Jun;24(2):789-805. TARTARINI G. PMID: 13363603

* Transformation of normal human fibroblasts into histologically malignant tissue in vitro. Science. 1956 Mar 23;123(3195):502-3. LEIGHTON J, KLINE I, ORR HC. PMID: 13298708

* Further evidence favoring the concept of the stem cell in ascites tumors of rats. Ann N Y Acad Sci. 1956 Mar 14;63(5):818-30. MAKINO S. PMID: 13314436

* Transformation of normal human fibroblasts into histologically malignant tissue in vitro. Science. 1956 Mar 23;123(3195):502-3. LEIGHTON J, KLINE I, ORR HC. PMID: 13298708

* The cytopathogenic effect of the Rous sarcoma virus on chicken fibroblasts in tissue cultures. Bull Johns Hopkins Hosp. 1955 Sep;97(3):248-65. LO WH, GEY GO, SHAPRAS P. PMID: 13284471

* [Morphology and evolutive possibility of the fibroblast in various inflammatory conditions.] Arch De Vecchi Anat Patol. 1955 Aug;23(2):501-24. MIGNANI E. PMID: 13283689

* [Stem-cell leukemia.] J Radiol Electrol Arch Electr Medicale. 1951;32(1-2):119-20. BRU, POUTANSANT, PLANEL. PMID: 14841727

* Reticulo-endotheliosis or stem-cell leukemia; a case report. Conn Med. 1949 Dec;13(12):1128-33, illust. EVANS TS, CIPRIANO AP, FERRELL EH Jr. PMID: 15397554

* Production of malignancy in vitro. XII. Further transformations of mouse fibroblasts to sarcomatous cells. J Natl Cancer Inst. 1950 Oct;11(2):351-75. SANFORD KK, EARLE WR, SHELTON E, SCHILLING EL, DUCHESNE EM, LIKELY GD, BECKER MM. PMID: 14795191



4. Transformation works both ways; just as stem cells can mutate and turn cancerous when exposed to chemical and other pathogens or infectious agents, mutated or cancerous stem cells can revert back to normal when exposed to normal stem cells - a fact recognized over 50 years ago.


* Transformation of carcinoma cells into fibroblasts. Acta Unio Int Contra Cancrum. 1956;12(4):459-60. BUENO P. PMID: 13381572

* The effect of aminopterin and partial exsanguination transfusion on a case of acute stem cell leukemia; a case report and review of the literature on these two procedures. Ann Intern Med. 1950 Jan;32(1):123-8. ROSS RT, SCHOEMPERLEN CB. PMID: 15404131

* The effect of serum ultrafiltrate on cultivated mast cells and fibroblasts from human skin. Science. 1954 Jan 15;119(3081):99. ZITCER EM, KIRK PL. PMID: 13122039



............Whether or not we support stem cell research, the therapies have been offered for decades in exclusive private clinics - and always will be, no matter what we do or think. (See my post above)

Last year, cancer was the #2 killer in America - the stats said 1 in 2 American men would get cancer, and 1 in 3 women. This year, cancer overtook heart diseases - cancer is now the #1 killer in America.

IMO - the "stem cell debate" is entirely synthetic. It's all about money - and the fact that insurance companies don't want to cover the costs of treatment.


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[edit on 21-2-2005 by soficrow]

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