Cutting-edge technology for flu vaccine development is called "reverse genetic engineering." It’s quick, easy and reliable, but it’s not being used
to create vaccines for the bird flu epidemic that’s threatening some parts of the world. Supposedly, it’s too expensive. Vaccine manufacturers say
profits will suffer if they pay royalties, so they still use the old, slow, unreliable "genetic reassortment" technology. As a result, some
estimates indicate a billion people may die world-wide from bird flu, including millions of Americans. Maybe a billion more will live to suffer
progressive degeneration and disability.
"People get sick; people die. But two biotechnology methods will change that. One is reverse genetics, which precisely replicates only the viral
genes that must be grown into vaccine. The other concerns multiplying that vaccine in mammalian cells. Both scramble the egg technique and slash
manufacturing time, allowing a quick and life-saving turnaround in production of new doses.
Reverse genetics will speed up things at the early stage of vaccine making. ...Reverse genetics means accurate replication first time, every time.
Webby's lab and others have done it in less than a week.
...The second speed-up will replace all those millions of eggs. ...Solomon says he believes the entire vaccination-production process can be cut "to
90 days or less." ...Thus a new strain might not be discovered until the flu season actually begins, yet we could have a fresh vaccine ready before
Stanford University’s May, 2004 paper “High Tech IP Issues in a Global Marketplace: Influenza in the US in the 20th Century” outlines the science and
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"Bird flu epidemic" media coverage in early 2003 said the problems were solved; the epidemic, when it hit, would be handled. Using reverse genetics,
vaccine development is fast and easy; the first vaccine for H5N1 bird flu was created within weeks in 1999. Development of a second vaccine for the
2002-2003 strain was even faster, at St. Judes Hospital in the USA and independently in the UK.
Unknown to most people, the flu vaccine situation deteriorated rapidly in the spring of 2004, but wasn’t covered by the media. Ordinary people
watching the situation were left with the impression that everything was under control, and all was well. Wrong. There’s a manufacturing hold-up. The
issues are murky and legal, and the spin doctors are rewriting the storyline almost daily.
Reverse genetics would save the day, said the early 2003 reports. Vaccine development now takes only a few days. Unlike old "genetic reassortment"
technology, reverse genetics is easy to use with the deadly H5N1 bird flu viruses. Plus, it is fast and reliable. Using reverse genetics technologies,
world vaccine production capacity can provide 750 million doses or 6 billion adjuvanted doses – within weeks.
By comparison: old "genetic reassortment" technology is slow, very difficult and subject to failure. It uses chicken eggs – which often are killed
by bird flu H5N1 strains. Best case scenario: 250 million doses in 6 months at full-out glitch-free world production capacity; nowhere near enough,
and way too slow.
Yet despite its deficiencies, old "genetic reassortment" technology still is being used to develop and manufacture vaccines for the coming bird flu
More than three groups own the Intellectual Property rights for reverse genetic engineering. One of the groups is a company called Medimmune.
Information about the other IP owners is not available. Reverse genetics technology was first developed in the 1980’s; ownership likely changed hands
since. This is the kind of technology Big Pharma would want to control.
If a vaccine that’s developed using reverse genetics goes into commercial production, then manufacturers need to negotiate royalties with all the IP
patent holders. MedImmune will waive royalties on its intellectual property for pandemic flu vaccines that are offered free to the public, but the
other IP patent holders remain invisible; none have made similar promises.
Before mid-November of 2004, not one vaccine manufacturer in the world had negotiated the rights to manufacture vaccines developed with reverse
genetics engineering technology. The World Health Organization apparently brokered a deal, but nothing is being discussed publicly – not the terms,
actual situation or implications.
The vaccine manufacturing hold-ups were known when President Bush made the Bio-Shield program a funding priority in the spring of 2004. Bio-Shield
commits $5.6 billion to develop vaccines for non-existent biological weapons, says William Schaffner, chairman of the preventive medicine department
at Vanderbilt Medical School in Nashville. "They're creating a very expensive program against diseases that don't exist anywhere in the world,"
said Dr. Schaffner.
In comparison, the Bush administration funded the "War Against Flu" with only $283 million, reports Dr. Anthony Fauci, director of the National
Institute for Allergy and Infectious Diseases.
Bird flu is an identified crisis with a known solution. But $5.3 Billion more tax dollars are committed to vaccine development for non-existent
biological weapons – leaving ordinary Americans without bird flu vaccines when bird flu is about to go epidemic.
"There is a need to raise the profile of pandemic preparedness as a matter of national security planning," warned Dr. Klaus Stöhr of the WHO, in a
news conference at the end of November’s closed Emergency flu meeting in Geneva.
Granted, the USA is not the only country without protection against bird flu. The whole planet is in the same boat. Some authorities are incensed;
others are not. The split is between interventionists on one side, and non-interventionists on the other. Interventionists believe everything possible
should be done to prevent the bird flu epidemic. Non-interventionists support policies of inaction and "benign neglect."
Non-interventionists say bird flu will take care of the world’s overpopulation problem: that flu is a legitimate form of natural selection. The weak,
old and already sick will be weeded out. When it’s all over, say non-interventionists, the world’s people will be stronger and healthier. Moreover,
they say, overpopulation creates an undue strain on the world’s finite resources, which will be relieved with depopulation.
Interventionists say research shows flu survivors are susceptible to progressive degeneration and disability that ends in heart disease and stroke.
Survivors will not be healthier they say, but will become burdens to health care and national economies. Moreover, depopulation policies misrepresent
the environmental situation to put corporate needs before ordinary people. Interventionists agree that finite resources – from energy to water and
food – are being depleted to the point of crisis, but they insist it is industry that’s over-using resources, not people.
Find links for infection-related heart disease and stroke at:
The explanations for the vaccine fiasco become more contradictory and murky every day, but the anticipated impacts are very clear:
A billion-odd people will die quickly; infected survivors will become disabled by heart disease then stroke. Instead of contributing to national
economies, these survivors will become economic and social burdens. The world’s nations will be overwhelmed by deaths and hospitalizations during the
epidemic, and then destroyed economically by the domino effect that will follow. An alliance of multinational corporations is positioned to storm the
The technology exists to prevent the crisis and the fallout. Yet the technology is not being used. All things considered, it looks, smells and feels
like a conspiracy.
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[edit on 27-11-2004 by Banshee]