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Today we found out that Tamiflu doesn't work so well after all. Roche, the drug company behind it, withheld vital information on its clinical trials for half a decade, but the Cochrane Collaboration, a global not-for-profit organisation of 14,000 academics, finally obtained all the information. Putting the evidence together, it has found that Tamiflu has little or no impact on complications of flu infection, such as pneumonia.
That is a scandal because the UK government spent £0.5bn stockpiling this drug in the hope that it would help prevent serious side-effects from flu infection. But the bigger scandal is that Roche broke no law by withholding vital information on how well its drug works. In fact, the methods and results of clinical trials on the drugs we use today are still routinely and legally being withheld from doctors, researchers and patients. It is simple bad luck for Roche that Tamiflu became, arbitrarily, the poster child for the missing-data story.
. . .
So does Tamiflu work? From the Cochrane analysis – fully public – Tamiflu does not reduce the number of hospitalisations. There wasn't enough data to see if it reduces the number of deaths. It does reduce the number of self-reported, unverified cases of pneumonia, but when you look at the five trials with a detailed diagnostic form for pneumonia, there is no significant benefit. It might help prevent flu symptoms, but not asymptomatic spread, and the evidence here is mixed. It will take a few hours off the duration of your flu symptoms. But all this comes at a significant cost of side-effects. Since percentages are hard to visualise, we can make those numbers more tangible by taking the figures from the Cochrane review, and applying them. For example, if a million people take Tamiflu in a pandemic, 45,000 will experience vomiting, 31,000 will experience headache and 11,000 will have psychiatric side-effects. Remember, though, that those figures all assume we are only giving Tamiflu to a million people: if things kick off, we have stockpiled enough for 80% of the population. That's quite a lot of vomit.
Roche has issued a press release saying it contests these conclusions, but giving no reasons: so now we can finally let science begin.
rickymouse
Tamaflu helps stop the replication of the virus. That helps people build up resistance to fight the flu by giving them more time to get up and running. It will do nothing for complications like pnemonia. It will not help people who have a compromised immune system, it only helps healthy individuals. It is not for that but I suppose the company producing it made us think it does that so they could boost sales.
White Pine needle tea does the same thing. It slows the replication of cells, it is not good for pregnant women though because it slows the replication of the cells in the child also. Drinking pine needle tea also slows our cells replication, it is a medicine not something you would use every day. It is high in vitamin c though. It is a medicine that is free.
Snarl
I always had my suspicions. Tamiflu was a 'reported cure' for Influenza (not a vaccine).
To my knowledge, there have been exactly zero pharmaceutical cures for viral infections discovered by science.
Snarl
I always had my suspicions. Tamiflu was a 'reported cure' for Influenza (not a vaccine).
To my knowledge, there have been exactly zero pharmaceutical cures for viral infections discovered by science.
Snarl
I always had my suspicions. Tamiflu was a 'reported cure' for Influenza (not a vaccine).
To my knowledge, there have been exactly zero pharmaceutical cures for viral infections discovered by science.
originally posted by: rickymouse
Here is some interesting information that just popped up. It is about virus replication and Ginseng. www.sciencedaily.com...
Now, I don't have any Korean Ginseng, but I do have a few ginseng plants growing in the woods on my land. There are only a few of them, but maybe enough to take one someday and make some tea for special occasions like the flu. I'm going to do some research on how to dry them properly, flu season isn't exactly in the time that I can go dig them up because they are covered with snow. I only have a few in the woods and wouldn't want to jeopardize their survival by selling them. There is quite a bit up north from here, they harvest them every summer. I can get some from some people I know that pick them I suppose.
I suppose the Pharma companies will be figuring a way to make this chemical into a pill to profit off of it. I suppose Arizona Iced tea prices will go up now.